Premier League picks from Miller: Everton vs Aston Villa, Leicester City vs Sheffield United, Crystal Palace vs Manchester United, and more

This could be the biggest day of the season in the Premier League (until next weekend).

With Manchester City and Liverpool now locked into UEFA Champions League places, there are just two spots left. The Europa League may now only go from fifth-to-seventh (if City wins this weekend), which means the race for European football is going to be tight as well. Wolves late draw Wednesday effectively takes them out of the Champions League hunt, so it looks like it will come down to Chelsea, Leicester City, and Manchester United.

Sheffield United can boost its European hopes in its first year back in the top flight with a win over undermanned Leicester today, but the Foxes are desperate to stay in that fourth spot.

Manchester United needs to shake off its late draw Monday, while Aston Villa needs a win to keep hope alive.

Which teams are going to take advantage today?

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ENGLAND PREMIER LEAGUE

Everton (+100) vs. Aston Villa (+265), draw (+255), 1 p.m. EDT (NBC Gold)

Leicester City (-114) vs. Sheffield United (+340), draw (+245), 1 p.m. EDT (NBCSN and Fubo.tv)

Crystal Palace (+1000) vs. Manchester United (-335), draw (+425), 3:15 p.m. EDT (NBCSN and Fubo.tv)

Southampton (+120) vs. Brighton (+250), draw (+225), 3:15 p.m. EDT (NBC Gold)

THE PICKS:

Aston Villa +0.5 (-121)

Sheffield United +0.5 (-107)

Southampton -0.25 Asian handicap (-114)

Manchester United/Palace over 2.5 goals (-139)

Anthony Martial to score (+117)

Marcus Rashford to score (+123)

Bruno Fernandes to score (+135)