Matches start at 7:30 am ET.
Is Premier League Match Week 13 the week when teams start making their moves in the table?
Liverpool has an eight point lead over Leicester City and Chelsea, with Manchester City nine points back, but the Reds have a trip to London to face Crystal Palace on hand.
There have not been too many more exciting games over the last half decade than the infamous "Crystanbul" comeback in 2014, when Liverpool threw away a 3-0 lead, just a week after the "Gerrard Slip" game against Chelsea.
Crystal Palace has been able to give the big boys of the Premier League trouble over the last few seasons, especially at home. Can the Eagles get something Saturday?
If they can, Manchester City and Chelsea will battle in the late game, with the winner able to close the gap to the top. Pep Guardiola's team has looked a shell of what is has over the last two seasons, but a lot can happen in the coming festive period.
Check Fubo.tv for channel listings
West Ham United (+325) vs. Tottenham (-125), draw (+320), 7:30 a.m. EST (NBCSN and Fubo.tv)
Tottenham ML (-125)
Arsenal (-210) vs. Southampton (+575), draw (+370), 10 a.m. EST (NBCSN and Fubo.tv)
Arsenal -0.5 first half (-105)
Arsenal -1.25 Asian handicap (+110)
Brighton & Hove Albion (+270) vs. Leicester City (+110), draw (+255), 10 a.m. EST (NBC Gold)
Leicester City ML (+110)
Crystal Palace (+650) vs. Liverpool (-240), draw (+390), 10 a.m. EST (NBC Gold)
Liverpool -1.25 Asian handicap (-105)
Everton (-265) vs. Norwich City (+700), draw (+400), 10 a.m. EST (NBC Gold)
Everton -1.5 (+120)
Over 3 goals Asian handicap (+100)
Manchester City (-225) vs. Chelsea (+550), draw (+400), 12:30 p.m. EST (NBC and Fubo.tv)
Manchester City first half -0.75 (+130)
Manchester City -1.25 Asian handicap (-105)
Over 3.5 goals (+115)
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