Matches are at 7:30 am and 10 am EDT,
After Aston Villa beat Everton 2-0 Friday, all three promoted sides in the Premier League already have a win.
There are still six teams without one after two matches, but two of them may get into the win column Saturday.
Frank Lampard's Chelsea team desperately needs to beat Norwich City, but the Canaries are going to be no pushover, especially at home.
The preseason hype around Leicester City may quickly lose steam if the Foxes do not get a victory over Sheffield United, but the home team will be bouncing after its first top flight win in over a decade.
In the EFL Championship, Fulham and Leeds United look to be the class of the division, and both can kick on Saturday with wins.
Check Fubo.tv listings for game channels
ENGLAND PREMIER LEAGUE
Norwich City (+320) vs. Chelsea (-125), draw (+290), 7:30 a.m. EDT (NBCSN and Fubo.tv)
Chelsea ML (-125)
Over 3 goals Asian handicap (-105)
Manchester United (-286) vs. Crystal Palace (+800), draw (+375), 10 a.m. EDT (NBCSN and Fubo.tv)
Manchester United -0.75 first half (+125)
Manchester United -1.5 (+110)
Mason Greenwood to score (IF HE STARTS) (+140)
Sheffield United (+240) vs. Leicester City (+125), draw (+215), 10 a.m. EDT (NBC Sports Gold)
Leicester City ML (+125)