NFL TNF: Mims picks 49ers vs Cardinals and looks for Jimmy Garoppolo and the Niner defense to give Kyler Murray trouble in the desert

9-6 so far this football season.

These are the key numbers for the game tonight between San Francisco at Arizona. Niners are 7-0. Cardinals are 3-4-1. The Niners are coming off a destruction of the Panthers, 51-13. Arizona lost to the Saints 31-9. Niners are the favorite at -10.5. The over/under total is 42.5. The money line is Niners -470 and Cardinals +380. Cardinals have won the last 4 games against the Niners.

The Niners have an outstanding running game and a formidable defense. The defense is ranked 1st in total D and against the pass. Jimmy Garoppolo's record as a starting QB is 15-2. Kyler Murray will have to use his leg to extend plays. His stats in the wins are impressive for a rookie QB.

The prop bet that looks appealing is Arizona under 16.5 for total points. The price is at -127. The total TDs by the Niners is listed at 2.5. The price is -190. This is a good play, but the price is high.

I have a lean toward the Niners to win this game. My play would be to lay the points. I am 9-6 in my selections on NFL Monday and Thursday. I have lost my last two leans, so I need to get back on track. Follow me on Twitter. Use the #GTLivechat and I will follow you back. Share your thoughts about tonight’s game.

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